Measuring and validation for isothermal solubility data of solid 2-(3,4-Dimethoxyphenyl)-5,6,7,8-tetramethoxychromen-4-one (nobiletin) in supercritical carbon dioxide

The Journal of Chemical Thermodynamics(2015)

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摘要
•Solubility of nobiletin in supercritical carbon dioxide was obtained.•Measured at T=(313, 323, and 333)K and at (17.97 to 31.40)MPa.•Correlated with empirical equation expressed in terms of SC-CO2 density.•Binary interaction parameters were fitted from experimental data using PR-EOS with Wong–Sandler mixing rule.•Thermodynamic consistency of phase equilibria data was evaluated using the G–D equation.
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关键词
Solubility,Nobiletin,Supercritical carbon dioxide,Dispersion,Modelling
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