Cell mediated immune responses following revaccination with an influenza A/H5N1 vaccine.

I N Mbawuike,Robert L Atmar,Shital M Patel,David B Corry,Patricia L Winokur,Rebecca C Brady,Wilbur H Chen,Kathryn M Edwards,C B Creech,Emmanuel B Walter,Sharon E Frey,Robert B Belshe,Johannes B Goll,Heather Hill,Wendy A Keitel

Vaccine（2016）

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摘要

•CMI responses occurred following administration of an inactivated A/H5N1 vaccine.•High dose vaccine increased the magnitude of CMI response only in the unprimed subjects.•IFN-γ nSFC levels correlated with IFN-γ concentrations in PBMC supernatants.

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关键词

Inactivated influenza vaccine,H5N1,Cell mediated immune response,Cytokine,Adjuvant

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