Targeted therapy of osteosarcoma with radiolabeled monoclonal antibody to an insulin-like growth factor-2 receptor (IGF2R).

David S Geller,Jonathan Morris,Ekaterina Revskaya,Mani Kahn,Wendong Zhang,Sajida Piperdi,Amy Park,Pratistha Koirala,Hillary Guzik,Charles Hall,Bang Hoang,Rui Yang,Michael Roth,Jonathan Gill,Richard Gorlick,Ekaterina Dadachova

CANCER RESEARCH（2019）

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摘要

This targeted approach offers the benefits of being independent of a specific pathway, a resistance mechanism, and/or an inherent biologic tumor trait and therefore is relevant to all OS tumors that express IGF2R.

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关键词

OS,Radioimmunotherapy,Insulin-like growth factor-2 receptor (IGF2R),Rhenium-188

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