1A.01: MUTATIONS AFFECTING THE CONSERVED ACIDIC MOTIF OF WNK1 CAUSE INHERITED NORMOTENSIVE HYPERKALEMIC ACIDOSIS.

H L Picard, N Thurairajasingam,Stephane Decramer,X Girerd, K Oshaugnessy,Paolo Mulatero,Gwenaelle Roussey,Ivan Tack,R J Unwin,Rosa Vargaspoussou,Xavier Jeunemaitre

JOURNAL OF HYPERTENSION（2015）

引用 4|浏览7

暂无评分

摘要

Objective:Mutations in the WNK1 and WNK4 genes have been shown to cause Familial Hyperkalemic Hypertension (FHHt, OMIM #145260), an inherited disorder combining arterial hypertension and hyperkalemia with metabolic acidosis. More recently, mutations in the KLHL3-CUL3 E3 ubiquitin ligase complex have

查看译文

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要