Genetic association study of the HLA class II alleles DRB1, DQA1, and DQB1 in patients with pharmacoresistant temporal lobe epilepsy associated with mesial hippocampal sclerosis

Wagner G Horta,Eduardo R Paradela,Andre Figueiredo,Isabella D Andrea Meira,Valeria Coelho Santa Rita Pereira,Claudia C Rego, Raquel De Carvalho Oliveira,Maria Emilia C Andraus,Glenda C Borges De Lacerda, Polyana Moura,Jorge P Marcondes De Souza,Carmen Lucia A Paiva,Soniza Vieira Alvesleon

Seizure（2015）

引用 9|浏览15

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摘要

•We aimed to study the relationship between HLA molecules and TLE-HS.•A significant increased trend in the frequency of HLA-DRB1*13:02 was found.•Possible role in genetic susceptibility of HLA in the mechanisms in TLE-HS.

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关键词

Temporal lobe epilepsy,Mesial sclerosis,Pharmacoresistant,Class II HLA,HLA DR

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