Ruscogenin suppresses mouse neutrophil activation: Involvement of protein kinase A pathway

Y N Lin,Rui Jia,Y H Liu,Yt Gao,L L Wang,J P Kou,Bo Yang Yu

The Journal of Steroid Biochemistry and Molecular Biology（2015）

引用 8|浏览1

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摘要

•Ruscogenin inhibited FMLP- and PMA-induced superoxide generation in neutrophils.•Ruscogenin inhibited mouse neutrophil activation via multiple pathways.•PKA was involved in the suppression of neutrophil activation by ruscogenin.

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关键词

Ruscogenin,Neutrophils,Superoxide anion,NADPH oxidase,Signaling pathways

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