228 Blood pressure in HIV-infected patients

Objectifve To determine the prevalence of hypertension in a cohort of HIV-infected patients (HIV+). Methods HIV+ patients were enrolled consecutively at ambulatory cardiology consultation. We evaluated: cardiovascular risk factors, office blood pressure, 24 hours ambulatory blood pressure monitoring (ABPM). We identified patients with known hypertension, masked hypertension and white-coat effect. Results 258 HIV+ patients (mean age 49 ± 7 ans, 91% men) were consecutively included in this study between 2005 and 2009. Cardiovascular risk factors were as follows: 52% had dyslipidemia, 51% were active smokers, 40% with known hypertension and 9% were diabetics. Body mass index of the entire cohort was 24 ± 4 kg/mΣ and 89% were under antiretrovirals. Data on blood pressure are depicted in Table 1. 19% (29) were discovered to have hypertension. Conclusion Hypertension is frequent in HIV-infected patients and more and more common with aging. The number of non-dipper HIV+ was high in this cohort. Studies on the impact of HIV infection and antiretrovirals on the autonomic nervous system should be performed. Parameters N = 258 Office systolic BP, mmHg 131 ± 19 Office diastolic BP, mmHg 81 ± 10 Mean 24h-systolic BP, mmHg 125 ± 13 Mean 24-diastolic BP, mmHg 77 ± 9 Daytime systolic BP, mmHg 129 ± 13 Daytime diastolic BP, mmHg 80 ± 9 Nighttime systolic BP, mmHg 115 ± 17 Nighttime diastolic BP, mmHg 68 ± 10 BP profile in known hypertensive patients N = 103 Number of patients with appropriate BP control, % 45% Number of patients with white-coat effect, % 17% Non dipper, % 43% in known hypertensive patients 39% in unknown hypertensive patients