Beijing clades of Mycobacterium tuberculosis are associated with differential survival in HIV-negative Russian patients

Yanina Balabanova,Vladyslav Nikolayevskyy,Olga Ignatyeva,Irina Kontsevaya,Svetlana Mironova,Alexander Kovalyov,Andrey Kritsky,Yulia Rodionova,Ivan Fedorin,Nicola Casali,Richard Hooper,Rolf D. Horstmann,Sergey Nejentsev,Sven Hoffner,Peter Nuernberg,Francis Drobniewski

Infection, Genetics and Evolution（2015）

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摘要

We conducted a prospective study to establish factors associated with survival in tuberculosis patients in Russia including social, clinical and pathogen-related genetic parameters. Specifically we wished to determine whether different strains/clades of the Beijing lineage exerted a differential effect of survival.

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关键词

Tuberculosis,Beijing family of strains,Clades,Survival,Russia

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