Treatment Of Hyperkalemia With Zs-9, A Selective Nonabsorbed Cation Exchange Resin, Does Not Lead To Hypomagnesemia: Results From Two Multicenter, Randomized, Double Blind, Placebo-Controlled Phase 3 Trials

Mohamed A. El-Shahawy,Henrik S. Rasmussen,Philip T. Lavin,Alex Yang,Wajeh Qunibi

Journal of the American College of Cardiology（2015）

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摘要

Hyperkalemia (HK) limits optimal use of cardioprotective RAAS inhibitors. Treatment of HK with the non-selective cation exchanger sodium polystyrene sulfonate (SPS) has limited efficacy and is associated with adverse effects such as hypocalcemia, hypomagnesemia and colonic necrosis, which are

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