Synthesis of Biaryl-Containing Medium-Ring Systems by Organocuprate Oxidation: Applications in the Total Synthesis of Ellagitannin Natural Products

Synthesis(2009)

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摘要
In this feature article we discuss the construction of biaryl-containing medium-sized rings by organocuprate oxidation and the application of this chemistry in the synthesis of members of the ellagitannin family of natural products. A concise and efficient total synthesis of the ellagitannin sanguiin H-5 is highlighted. Studies towards the synthesis of elaeocarpusin are also presented.
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关键词
cuprates,total synthesis,ring-closing,natural products,biaryls
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