Bio-relevant complexes of novel N 2 O 2 type heterocyclic ligand: Synthesis, structural elucidation, biological evaluation and docking studies

T Arun,S Packianathan,M Malarvizhi,Rajendran Antony,Natarajan Raman

Journal of Photochemistry and Photobiology B: Biology（2015）

引用 22|浏览4

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摘要

•Novel bio-relevant complexes have been synthesized.•The synthesized bio relevant complexes are efficient metallointercalators.•Molecular docking model supports the intercalative mode of action with DNA.•Developing novel metal based drugs.

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关键词

N2O2-Schiff base,DNA binding,DNA cleavage,Anti-pathogenic activity,Molecular docking

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