Comparative in vitro susceptibility of a novel fluoroquinolone antibiotic candidate WFQ-228, levofloxacin, and moxifloxacin against Mycobacterium tuberculosis

Min Qiao,Weicong Ren,Haiping Guo,Fengmin Huo,Yuanyuan Shang,Yufeng Wang,Mengqiu Gao,Yu Pang

International Journal of Infectious Diseases（2021）

引用 2|浏览8

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摘要

•WFQ-228 is more efficacious than LFX in isolates with specific mutations.•The bactericidal effect is more frequently observed in MFX-susceptible isolates.•The heterogeneity in MICs of isolates with different mutations is noted across FQs.

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关键词

WFQ-228,Mycobacterium,gyrA,Susceptibility

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