Human Acyl-CoA: Cholesterol Acyltransferase Inhibitory Effect of Flavonoids from Roots of Glycine max (L.) Merr

Jinhwan Lee,Wooduck Seo, Seonghun Jeong,Taesook Jeong,Woosong Lee,Kihun Park

Journal of Applied Biological Chemistry（2006）

引用 34|浏览2

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摘要

Isoflavones 1-3 and pterocarpans 4-8 were isolated from methanol extract of roots of Glycine max. In inhibitory effect against human acyl-CoA:cholesterol acytransferase (ACAT)-1 and ACAT-2, glyceollin I 5 showed potent hACAT-1 () and hACAT-2 () inhibitory activities.

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