Reduced red blood cell deformability over time is associated with a poor outcome in septic patients

Katia Donadello,Michael Piagnerelli,Giulia Reggiori,Leonardo Gottin,Sabino Scolletta,Giovanna Occhipinti,Karim Zouaoui Boudjeltia,Jean Louis Vincent

Microvascular Research（2015）

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摘要

•Critically ill patients, particularly those with sepsis, have altered RBC rheology already at ICU admission.•Deformability is reduced and aggregation increased in septic compared to non-septic patients.•Reduced RBC deformability over time is associated with poor outcome.

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关键词

Sepsis,Erythrocyte,Microcirculation,Laser-assisted Optical Rotational Cell Analyzer (LORCA),Rheology,Deformability

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