Interfacial and micellar properties of mixed systems of tricyclic antidepressant drugs with polyoxyethylene alkyl ether surfactants

Colloids and Surfaces A: Physicochemical and Engineering Aspects(2014)

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摘要
•Micellar and interfacial studies of amphiphilic drugs with nonionic surfactants.•Drug-surfactant mixtures show improved surface active properties.•Synergism is observed in all mixed systems.•Hydrophobicity plays an important role in micellization.
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关键词
Nonionic polyoxyethylene alkyl ether surfactants,Tricyclic antidepressants,Surface tension,Fluorescence,Cloud point,Synergism
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