Deficiency Of The Stimulatory G Protein Alpha-Subunit Gs (Alpha) Leads To Reduced Apoa-I Mediated Cellular Lipid Efflux And Impaired Abca1-Dependent Nascent Hdl Biogenesis Pathway

It has been suggested that initial apoA-I binding to ABCA1 is coupled to the activation of signal transduction pathways, allowing excess cholesterol removal from tissues. However, the role of the h...