Abstract 141: Impact of Prehospital Advanced Care on Regional Brain Oxygen Saturation at Hospital Arrival and Neurological Outcomes at 90 Days in Patients with Out-of-Hospital Cardiopulmonary Arrest

Introduction: In recent years, brain resuscitation has gained importance over cardiopulmonary resuscitation for the prognosis of patients experiencing cardiac arrest. Objective: The aim of this study was to investigate the impact of pre-hospital advanced care on the brain resuscitation after out-of-hospital cardiac arrest (OHCA). Methods: The J-POP registry is a prospective multicenter cohort study to test whether regional brain oxygen saturation (rSO2) predicts neurological outcomes after non-traumatic OHCA, and we previously demonstrated good neurological outcomes were associated with high rSO2 (>40%) at hospital arrival. From this database, the data on patients with ROSC at hospital arrival were analyzed. Primary endpoints were high rSO2 (>40%) at hospital arrival and good neurological outcomes (CPC 1 / 2) at 90 days. Results: Of the 1921 OHCA patients included in the J-POP registry database, 148 patients with ROSC at hospital arrival were included in this study; of these, 109 (73%) had high rSO2 (>40%...