Relation between Prostatic Calcification and Urolithiasis

Prostatic calculi are common finding in radiographic examination but the true incidence and the clinical significance are not clearly known. We investigated the prevalence of prostatic calculi and the relationship between prostatic calcification and urolithiasis. From January 2007 to July 2009, a database of 305 consecutive subjects who aged more than 30-year old and had regular health check in our hospital. The prostatic calculi and urinary stones were confirmed by non-enhanced CT. According to the presence of prostatic calculi, they were divided into two groups and the relationship with urolithiasis was determined using the statistical analysis. Among 305 male subjects, prostatic calculi were found in 97 (31.9%) that revealed with linear trend with aging (r=0.928, p=0.023), while asymptomatic upper urinary tract stones were found in 45 (14.9%). A significance difference was found in mean age (p<0.001), but there were no difference in prevalence of diabetes mellitus (DM), hypertension (HT), and body mass index (BMI). In prostatic calculi group, 24 (24.7%) of subjects had urolithiasis previously unknown, while only 21 (10.1%) had urinary stone in non-prostatic calculi group. The prevalence of urolithiasis was significantly higher in men with prostatic calcification than those without prostatic calcification (OR=2.92, 95% CI: 1.53-5.58, p=0.001). There were no significant differences in serum chemistry between two groups. Among the 45 urolithiasis patients, there were no significant differences in the mean stone size according to the presence of prostatic calcification. Our data showed that the prostatic calcification was prevalent up to about 31.9% and frequently combined with upper urinary tract stones. These results indicate that the evaluation for urolithiasis might be needed in patients with incidentally detected prostatic calcification.