A novel beer fermented by kefir enhances anti-inflammatory and anti-ulcerogenic activities found isolated in its constituents

•A craft beer made with kefir grains was prepared.•Kefir beer was able to reduce inflammation and ulceration in rat models.•Aqueous kefiran purified from the kefir grains had similar results to kefir beer.•Both kefir beer and kefiran seem to act via prostaglandin regulation.•Kefir beer improved the health benefits related to kefir or beer consumption alone.