SYNTHESIS OF DIHYDROPYRIMIDINONES: AN IMPROVED CONDITIONS FOR THE BIGINELLI REACTION

A Vijender Reddy,Y Venkateswarlu,K Ravinder,V L Niranjan Reddy

Heterocyclic Communications（2002）

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摘要

A mild and selective method for the synthesis of dihydropyrimidinones using CBr4 in methanol in the Biginelli three component cyclocondensation reactions has been developed. Yields are significantly higher than utilizing classical Biginelli reaction conditions.

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