Insights into the nature of uranium target proteins within zebrafish gills after chronic and acute waterborne exposures

New data on the nature of the protein targets of uranium (U) within zebrafish gills were collected after waterborne exposure, with the aim of a better understanding of U toxicity mechanisms. Some common characteristics of the U protein target binding properties were found, such as their role in the regulation of other essential metals and their phosphorus content. In total, 21 potential protein targets, including hemoglobin, are identified and discussed in terms of the literature. Environ Toxicol Chem 2016;35:736-741. (c) 2015 SETAC