The p66 Shc knockout mice are short lived under natural condition: P66 Shc is detrimental in lab but required in wild
Pier Giuseppe Pelicci,Francesca Cirulli,H P Lipp,Irmgard Amrein,Sarah Notzli,Enrica Migliaccio,Gino Cortopassi,Jon J Ramsey,Kevork Hagopian,Massimo Stendardo,Mirella Trinei,Inga I Poletaeva,Ina Berniakovich,Alessandra Berry,Marco Giorgio Aging Cell（2011）
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