Memory impairment in patients with clinically isolated syndrome

Background: Multiple sclerosis (MS) is a chronic disease affecting young adults, manifesting beside motor and visual deficits also by cognitive impairment, including memory. Recent studies indicated that cognitive impairment can be present already in patients with clinically isolated syndrome (CIS), who are at higher risk of developing CDMS (clinically definite MS) but specific studies focused on memory in CIS patients are lacking.