Glycoconjugates of polyhedral boron clusters
Journal of Organometallic Chemistry(2015)
摘要
The potential medicinal applications of boron-based compounds have been well established. Among the medicinal applications of boron, its use for the treatment of cancer via boron neutron capture therapy (BNCT) is the most promising. Although a variety of approaches have been evaluated for adequate boron delivery to the cancer tissues for successful cancer therapy, this review focuses on the synthesis of carbohydrate-based boron delivery platforms. Recent advances in the synthesis and utilization of glycoconjugates for boron delivery has been reported.
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关键词
Boron clusters,Carbohydrate,Carbohydrate mimetics,Cancer therapy,Glycoconjugates,Medicinal chemistry
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