ChemInform Abstract: An Expeditious Synthesis of Biologically Important myo‐Inositol Phosphorothioates.

C E Dreef, G W Mayr, J P Jansze,H C P F Roelen,G A Van Der Marel,J H Van Boom

Cheminform（1993）

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摘要

Abstract The myo -inositol phosphorothioates 6 , 9 , 12 , and 17 were readily accessible from properly protected precursors by phosphitylation with N,N -diisopropyl dibenzyl phosphoramidite ( 1 ), subsequent in situ sulfurization of the intermediate phosphite triesters with phenacetyl disulfide ( 3 ), and removal of all benzyl protecting groups.

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expeditious synthesis,myo-inositol

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