ChemInform Abstract: Synthesis of 2,5‐Disubstituted‐3‐cyanoindoles.

Mark A Bobko,Karen A Evans,Arun C Kaura,Leanna E Shuster,Daishi Su

Cheminform（2012）

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摘要

A three-step sequence including selective iodination and ring closure with KOtBu via a Modified Madelung reaction yields iodo precursors of type (VI), which can be coupled with arylboronic acids.

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关键词

3-Cyanoindoles,2,5-Disubstituted-3-cyanoindoles,Modified Madelung reaction,Selective iodination,Synthesis

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