ChemInform Abstract: Total Synthesis of rac-Silandrin, an Antihepatotoxic Flavanolignan.

S. ANTUS,E. BAITZ-GACS, A. GOTTSEGEN,T. KOVACS, J. SZUNYOG,T. S. TOTH,H. WAGNER

Cheminform（2010）

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摘要

The first synthesis of racemic silandrin (rac-1), which shows significant antihepatotoxic activity, has been accomplished via the key intermediate 9 prepared from the readily available starting materials caffeic acid ethyl ester (4) and coniferyl alcohol (5).

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关键词

FLAVANOLIGNAN,SILANDRIN,ANTIHEPATOTOXIC ACTIVITY,1,4-BENZODIOXANE

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