Dynamic microglial modulation of spatial learning and social behavior

Luisa Torres,Joan Danver,Kyungmin Ji,Jeremy T. Miyauchi,Danling Chen,Maria E. Anderson,Brian L. West,John K. Robinson,Stella E. Tsirka

Brain, Behavior, and Immunity（2016）

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摘要

•Local hippocampal microglial depletion alters learning and social behavior.•Systemic microglia depletion alters learning but not social behavior.•These behavioral changes are reversed upon microglial repopulation.

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关键词

Microglia depletion,Hippocampus,Memory,Clodronate,Csf1 inhibition

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