Design, synthesis and biological evaluation of novel arylpiperazine derivatives on human prostate cancer cell lines
Chinese Chemical Letters（2016）
摘要
A novel series of arylpiperazine derivatives was synthesized and evaluated for their cytotoxic activity against three human prostate cancer cell lines. Among all, compounds 8, 10 and 20 exhibited strong cytotoxic activities against the tested cancer cells.
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关键词
Synthesis,Arylpiperazine derivatives,Cytotoxic activity,CCK-8,Structure–activity relationship
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