Study on intestinal transport of Veratrum alkaloids compatible with Panax ginseng across the Caco-2 cell monolayer model by UPLC-ESI-MS method

In this study, Caco-2 cell monolayer model was used to study the transport of the Veratrum alkaloids in different proportions with Panax ginseng. A specific UPLC-ESI-MS method is developed for the determination of Veratrum alkaloids on intestinal transport with berberine as internal standard. Three influencing factors and the interaction mechanism between Veratrum nigrum and Panax ginseng were investigated.