SECONDARY BENEFITS OF ALCOHOL REDUCTION WITH NALMEFENE

Alcohol and Alcoholism(2015)

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摘要
The opioid system modulator nalmefene reduce average daily total alcohol consumption, number of heavy drinking days, and improve liver function and clinical status in alcohol-dependent patients. We investigated the effect of alcohol reduction with nalmefene 18 mg on alcohol dependence features, drinking consequences, and mood in two 6-month randomized, double-blind, placebo-controlled, studies (NCT00811720; NCT00812461) in alcohol-dependent patients. …
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