Association of status redox with demographic, clinical and imaging parameters in patients with Huntington's disease

Marisol Penasanchez,Gretel Riveronforment,Tatiana Zaldivarvaillant, Alexis Sotolavastida, Judith Borrerosanchez,Gloria Larafernandez, Enrique M Estebanhernandez,Zenaida Hernandezdiaz,A Gonzalezquevedo,Isabel Fernandezalmirall, Claudia Perezlopez, Yaisa Castillocasanas,Olivia Martinezbonne, Amelia Cabrerarivero, Leyenis Valdesramos, Rosa Guerrabadia,Rebeca Fernandezcarriera,Maria Caridad Menendezsainz,Sergio Gonzalezgarcia

Clinical Biochemistry（2015）

引用 20|浏览8

暂无评分

摘要

Huntington's disease (HD) is an autosomal dominant, progressive neurodegenerative disorder, caused by an expanded trinucleotide CAG sequence of the huntingtin (Htt) gene, which encodes a stretch of glutamines in the Htt protein. The mechanisms of neurodegeneration associated with the accumulation of Htt aggregates still remains unclear.

查看译文

关键词

Huntington's disease,Oxidative stress,Reductase glutathione,Reduced glutathione,Advanced oxidative protein products,Age at symptom onset,Motor scale,Caudate atrophy

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要