0736. Role of C AMP in PAF-induced intestinal endo-and epithelial dysfunction

I Lautenschläger,K Zitta, J Sarau,H Dombrowsky, YL Wong,M Albrecht,S Uhlig,I Frerichs,N Weiler

Intensive Care Medicine Experimental（2014）

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摘要

Platelet activating factor (PAF) induces vascular barrier breakdown and intestinal failure that contribute to the development of sepsis. The exact cellular mechanisms are not well understood.

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关键词

Dextran, Adenylate Cyclase, Phosphodiesterase, Platelet Activate Factor, Intracellular cAMP

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