Sub-lethal ionizing radiation alters Foxp3 expression in CD4+ T regulatory (Treg) cells in vitro and in vivo

Anita Kumari,Samantha Simon,Charlie Garnett-Benson

Journal for ImmunoTherapy of Cancer（2015）

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摘要

Meeting abstracts The use of sub-lethal radiation has been shown to alter cell phenotype and gene expression. T regulatory (Treg) cells are phenotypically defined as being CD4+CD25+ Foxp3+ T cells and are known to suppress the function of CD8+ cytotoxic T lymphocytes (CTLs). Inhibiting the

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关键词

Public Health,Gene Expression,Treg Cell,Radiation Treatment,Cell Phenotype

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