PS8 - 42. Basal endogenous glucose production and insulin levels are reduced 2 weeks after bariatric surgery with no effect on hepatic and peripheral insulin sensitivity

Barbara A. de Weijer,Edo Aarts,Ignace M.J. Janssen,Arnold van de Laar,Karin Kaasjager,Mariette T. Ackermans,Eric Fliers,Mireille J. Serlie

Nederlands Tijdschrift voor Diabetologie（2015）

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摘要

Bariatric surgery has very early metabolic effects on glucose metabolism before the occurrence of clinically significant weight loss. This suggests an acute effect of the surgery itself, i.e. bypassing the nutrient flow from the proximal gastrointestinal tract. We hypothesized that Roux-en Y gastric bypass surgery (RYGB) ameliorates glucose metabolism by increasing hepatic and peripheral insulin sensitivity.

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关键词

Glucose Metabolism,Insulin Level,Acute Effect,Basal Insulin,Significant Weight Loss

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