No Association Between Hla Class 11 Genes And Testicular Germ Tumour (Tgct) With Genotyping Of The Hla-Region On Chromosome 6p21 And Haplotype Sharing Analysis

GERM CELL TUMOURS V(2002)

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摘要
Association with HLA, in particular class II genes (DQB1, DRB1), has been suggested as one of the genetic factors involved in TGCT development [1]. The present study used a marker haplotyping method in trios (parents or spouse and child) to replicate the previous findings, obtained through HLA typing.
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关键词
Testicular Cancer, Testicular Germ Cell, Transmission Disequilibrium Test, Haplotype Sharing, Founder Haplotype
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