3,3,4,4-Tetraethoxybutyne - An Excellent Starting Material For The Synthesis Of Range Of Functionalized Compounds

The title compound is a stable chemical entity, easily prepared on a large scale using cheap chemicals. The compound is densely functionalized, and by taking advantage of the chemical properties of the various functional groups, a variety of compounds have been synthesized. Some syntheses involve deprotection of the ketal moiety to form the corresponding alpha, beta-unsaturated acetylenic ketones, which appear to react with nucleophiles in a Michael fashion. This has enabled us to develop a new furan synthesis.