PM448 Ventricular non-compaction is prevalent in patients with single ventricle physiology but does not alter ventricular function

Global heart(2014)

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摘要
O ST E R A B ST R A C T S LVAC was evident in 78 (%) patients and LVNC in 15 (%). The most prevalent abnormality was mid-ventricular septal trabeculation in 40 patients.. Patients with LVNC had significantly higher indexed end-diastolic (97+/-24 mL/m vs. 119+/-29 mL/m; p1⁄40.006) and end-systolic volumes (58+/-19 mL/m vs. 47+/-16 mL/m; p 1⁄4 0.03) compared to normally compacted ventricles. Ejection fraction did not significantly differ between the LVAC and normally compacted patients. (EF 60+/-6% vs. abnormally compacted EF 52+/-1; p 1⁄4 0.30). Age, gender or presence of bicuspid aortic valves did not correlate with presence of NC. In a subset of 148 cases, detailed short axis LV cine stacks were performed, revealing abnormalities of the mitral valve leaflets in 10, papillary muscles in 17 and myocardial clefts in 28 patients. Conclusion: Abnormal ventricular morphology is prevalent in CoA and should be considered in addition to the known valvular and vascular complications. Ventricular noncompaction correlates with increased end-diastolic volumes and may impact on ventricular function over time. Disclosure of Interest: None Declared
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