Biocompatible packagings for fully implantable multi-panel devices for remote monitoring of metabolism

This paper compares three different biocompatible packaging covers suitable to support full implantation of multipanel sensors for remote monitoring of metabolism. The three covers have been designed, realized and implanted in mice for 30 days. ATP and neutrophil concentrations have been measured at the implant site after the device was explanted, to assess the level of biocompatibility of the device.