Comparison of variations detection between whole-genome amplification methods used in single-cell resequencing

    pp. 372015.

    Cited by: 64|Bibtex|Views3|Links
    Keywords:
    malbacnext generation sequencing

    Abstract:

    Single-cell resequencing (SCRS) provides many biomedical advances in variations detection at the single-cell level, but it currently relies on whole genome amplification (WGA). Three methods are commonly used for WGA: multiple displacement amplification (MDA), degenerate-oligonucleotide-primed PCR (DOP-PCR) and multiple annealing and loop...More

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