In vitro biomarker discovery in the parasitic flatworm Fasciola hepatica for monitoring chemotherapeutic treatment

EuPA Open Proteomics(2014)

引用 16|浏览13
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摘要
•Fasciola hepatica excretory/secretory products can be used as biomarkers.•Two panels of biomarkers identified in response to triclabendazole sulphoxide.•A sub-lethal, under dosed, panel (calreticulin, the Cat L proteases and enolase).•A lethal panel (actin, gelsolin, DJ-1 and triose phosphate isomerise).
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关键词
TCBZ,TCBZ-SO,TCBZ-R,ES,Con,SL,L,CRT,Cat L
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