GammaKnife Radiosurgery for Melanoma Brain Metastases

Purpose: The objective of this study is to report the combined experience at Johns Hopkins University (JHU) and the Miami Neuroscience Center (MNC) in treating brain metastases from melanoma with stereotactic radiosurgery (SRS). Methods and Materials: Prospectively collected clinical and demographic data on patients with melanoma treated with Gamma Knife (GK) at JHU between 2003 and 2007 and the MNC between 1993 and 2009 were reviewed. Cox proportional hazards regression and Kaplan Meyer analyses were used to compare survival by clinical and demographic characteristics and treatment.