Network Model of Acetobacter Xylinum Cellulose Intercalated by Drug Nanoparticles

It was shown that Acetobacter xylinum cellulose gel-films can sorb silver and selenium nanoparticles stabilized by N-poly(vinyl-2-pirrolidone). The structure of original cellulose matrix, isolated nanoparticles and cellulose with sorbed nanoparticles was characterized by electron diffraction, electron microscopy, small- and wide-angle x-ray scattering methods, and atomic force microscopy. It was found that in static culture Acetobacter xylinum bacterium (strain VKM B-880) may synthesize high-molecular cellulose with narrow molecular weight distribution and a considerable number of carbon sources. The structures of cellulose microfibrilles and ribbons correspond mainly to polymorphous 1, modification. We concluded from structural studies that textured cellulose films were formed. The sorption conditions of poly(vinylpyrrolidone)-Se-o and poly(vinylpyrrolidone)-Ag-o nanoparticles were optimized to obtain a cellulose template that can be used in medical practice.