Custom Thermoformed Trays In The Treatment Of Denture Stomatitis

The aim of this study was to evaluate the effect of miconazole gel delivered on a custom thermoformed tray as an overnight drug holder appliance in denture stomatitis treatment, in comparison with classic application as recommended by manufacturer. The investigation included 44 upper denture wearers, diagnosed with denture stomatitis. The experimental group (n = 22) applied 2% miconazole gel in custom tray for overnight wear. The control group (n = 22) applied 2,5 ml of the same drug 4 times a day in their mouth. Intensity of inflammation and infection was evaluated. The clinical tests that were used were: inflammation intensity according to Newton, extent of palatal mucosal erythematous surface below denture, digital thermometry, and swabs for Candida albicans cultures. Oldness and hygiene status of dentures were recorded, as well as habit of overnight denture wearing. The investigation revealed that denture stomatitis healed faster and better in the experimental group compared to control group. Greater Candida albicans culture colony count reduction was observed in experimental group, which suggests more efficient elimination of Candida albicans from the mouth with novel method. This method motivates patients to adhere to treatment and appliance hygiene instructions. Custom splint as occlusive drug delivery showed to be more effective and more convenient for the patients than the same antimicotic drug, classically delivered, which might be clinically relevant in treatment of denture stomatitis.