Blood protein predictors of brain amyloid for enrichment in clinical trials?

Nicholas Ashton,Steven Kiddle,John Graf,Malcolm Ward,Alison Baird,Abdul Hye,Sarah Westwood, Karyuan Vivian Wong,R Dobson,Gil D Rabinovici,Bruce L Miller, Howard J Rosen,Andrew Torres,Zhanpan Zhang,Lennart Thurfjell,Antonia Covin,Cristina Tan Hehir,David Baker,Chantal Bazenet,Simon Lovestone

Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring（2015）

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摘要

A single blood protein, FGG, combined with age, was shown to relate to NAB and therefore could have potential for enrichment of clinical trial populations.

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关键词

Plasma,β amyloid,Proteomics,Alzheimer's disease,Biomarker,Fibrinogen γ-chain,Clinical trials

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