Probing Telopeptide-Induced Collagen-Collagen Interactions Using Optical-Tweezers-Based Microrheology

Tuba Altindal,Marjan Shayegan,Evan Kiefl,Nancy R. Forde

Optics in the Life Sciences (2015), paper OtM3E.3（2015）

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摘要

The local viscoelasticity was compared between full-length and telopeptide-removed collagen solutions using optical-tweezers-based microrheology. An enhanced modulus at higher concentrations in full-length collagen solutions suggests contributions from telopeptide-associated transient crosslinks.

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