Trial sequential analysis of the efficacy of Fasudil in Chinese patients with pulmonary hypertension

Huan Wang,Jiangbo Zhang,Haiyan Chen,Chunyan Tan,Houxiang Hu

Journal of the American College of Cardiology（2015）

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摘要

Activation of Rho-A/Rho-kinase pathway found recently is one of the pathogenic mechanisms on pulmonary hypertension. It is necessary to evaluate the efficacy of Rho-kinase inhibitor Fasudil for the treatment of pulmonary hypertension based on principle of Meta-analysis and trial sequential analysis

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