The receptor for advanced glycation end products in ventilator-induced lung injury

    Intensive care medicine experimental, Volume 2, Issue 1, 2014, Pages 22

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    Keywords:
    Acute lung injury Mechanical ventilation Receptor for advanced glycation end products Inflammation Innate immunity

    Abstract:

    RAGE was not a crucial contributor to the pro-inflammatory state induced by MV. However, the presence of sRAGE limited the production of pro-inflammatory mediators in our 2-hit model of LPS and high tidal volume MV.

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