The receptor for advanced glycation end products in ventilator-induced lung injury
Intensive care medicine experimental, Volume 2, Issue 1, 2014, Pages 22
Acute lung injury Mechanical ventilation Receptor for advanced glycation end products Inflammation Innate immunity
RAGE was not a crucial contributor to the pro-inflammatory state induced by MV. However, the presence of sRAGE limited the production of pro-inflammatory mediators in our 2-hit model of LPS and high tidal volume MV.
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