Pituitary Hyperplasia and Van Wyk Grumbach Syndrome: A Consequence of Chronic Untreated Congenital Hypothyroidism

Deep Dutta,Manoj Kumar,Rajesh Jain,Anubhav Thukral,Sujoy Ghosh,Satinath Mukhopadhyay,Subhankar Chowdhury

Journal of the ASEAN Federation of Endocrine Societies（2014）

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摘要

An eight-year, 4-month old Indian girl with low IQ and delayed milestones, presented with headache (4 years), breast development (4 months), and menstrual bleeding for 22 days. Examination revealed short stature [height: 91.5 cm; SD score: -5.59], coarse dry skin, umbilical hernia (arrow), delayed reflexes, Tanner’s stage-3 breasts, absent pubic and axillary hair

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