Impact of HLA-class I alleles on response to HCV treatment in a cohort of Egyptian patients

Howayda E Gomaa, M Mahmoud,Nevine E Saad,Amal Saadhussein,Eman H Thabet,H Farouk,Dina Kandil,A Heiba,Wael Hafez,S Ismail

Journal of Genetic Engineering and Biotechnology（2014）

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摘要

Extensive allele diversity is observed in HLA associations with response to HCV combined therapy (pegylated interferon+ribavitin) in different global ethnic populations. The aim of the study is to assess the frequency and association of certain HLA-class I alleles in Egyptian persons with persistent HCV and others with sustained viral response (SVR).

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关键词

HCV genotype 4,HLA class I,Egypt

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